Antithrombin III Recombinant Rabbit mAb (SDT-294-303)

產(chǎn)品型號：S0B3117

更新時(shí)間：2025-07-11

廠商性質(zhì)：生產(chǎn)廠家

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

Antithrombin III （ATIII） is a nonvitamin K-dependent protease that inhibits coagulation by neutralizing the enzymatic activity of thrombin （factors IIa, IXa, Xa）. Antithrombin III activity is markedly potentiated by heparin, the principal mechanism by which both heparin and low–molecular-weight heparin result in anticoagulation. Thrombin–antithrombin complex （TAT） is a protein complex of thrombin and antithrombin. It is a marker of net activation of coagulation. TAT is formed in response to the high thrombin level caused by coagulation following a ruptured vessel. Since thrombin is rapidly bound by antithrombin, TAT is a useful measure for thrombin level in the blood. Thrombin can pass the blood–brain barrier, destroying neurons and potentially causing cerebral edemas. The half-life of TAT is approximately 15 minutes.

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