Alexa Fluor? 647 Human Anti-Human CD40 Antibody (S-R443)

產(chǎn)品型號：S0B1615

更新時間：2025-07-11

廠商性質(zhì)：生產(chǎn)廠家

訪問量：33

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD40 is a member of the tumor necrosis factor receptor superfamily and is primarily involved in regulating immune responses. It is highly expressed on cells such as B cells, dendritic cells （DCs）, and monocytes, and plays a crucial role in linking innate and adaptive immunity. CD40 signaling is a key trigger in the maturation process of monocytes, mainly driving differentiation into M1-type macrophages and DCs. On DC surfaces, CD40 is involved in promoting the production of cytokines and chemokines, inducing the expression of costimulatory molecules, and enhancing antigen cross-presentation. CD40 is also expressed on various types of cells, including fibroblasts, endothelial cells, and certain hematopoietic and epithelial tumor cells. In the context of CAR-T cell therapy, the expression of CD40L on the surface of CAR-T cells has been explored to enhance their anti-tumor functions.

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