Alexa Fluor? 647 Mouse Anti-Mouse CD64 Antibody (S-R614)

產(chǎn)品型號(hào)：S0B5015

更新時(shí)間：2025-07-12

廠商性質(zhì)：生產(chǎn)廠家

訪問量：29

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD64, also known as FcγRI, is a high-affinity receptor for the Fc fragment of IgG and belongs to the immunoglobulin superfamily. It is primarily expressed on the surface of monocytes, macrophages, dendritic cells, and neutrophils. Under normal conditions, CD64 expression on neutrophils is low, but it rapidly increases within 4-6 hours upon stimulation by bacterial lipopolysaccharides （LPS）, cytokines, or other inflammatory mediators. This upregulation makes CD64 a valuable biomarker for diagnosing bacterial infections, sepsis, and other inflammatory conditions. It has higher sensitivity and specificity compared to traditional markers like white blood cell count, C-reactive protein （CRP）, and procalcitonin （PCT） for distinguishing bacterial infections from viral infections or non-infectious inflammation. Additionally, CD64 can be used to monitor treatment efficacy, predict postoperative infections, and guide antibiotic therapy.

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