Alexa Fluor? 647 Armenian hamster Anti-Mouse CD103 Antibody (S-R692)

產(chǎn)品型號(hào)：S0B5136

更新時(shí)間：2025-07-12

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD103, also known as integrin αEβ7, is a transmembrane heterodimeric receptor primarily expressed on the surface of certain immune cells, including intraepithelial lymphocytes （IELs）, tissue-resident memory T cells, and dendritic cells. It plays a crucial role in cell adhesion and migration by binding to E-cadherin, a protein abundant in epithelial cells, thereby facilitating immune cell retention within mucosal tissues such as the skin, lung, and gastrointestinal tract. In cancer immunology, CD103 is associated with immune checkpoint pathways and has been identified as a potential biomarker for predicting responses to immunotherapies, such as anti-PD-1 treatments. Additionally, CD103+ dendritic cells are known for their ability to cross-present antigens to CD8+ T cells, enhancing adaptive immune responses.

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