Alexa Fluor? 647 Rat Anti-Mouse CD199 Antibody (S-R715)

產(chǎn)品型號：S0B5190

更新時(shí)間：2025-07-12

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD199, also known as CCR9, is a member of the G protein-coupled receptor （GPCR） family and functions as a chemokine receptor. It is a ~42 kDa seven-transmembrane protein primarily involved in T cell development in the thymus and gut-associated immune responses. CCR9 is expressed on T lymphocytes and is upregulated in response to retinoic acid, which is produced by dendritic cells, facilitating the migration of T cells to gut-associated tissues. Its specific ligand is CCL25 （TECK）, and the interaction between CCR9 and CCL25 plays a crucial role in the recruitment and maturation of thymocytes. Additionally, CCR9 is differentially expressed in T lymphocytes of the small intestine and colon, suggesting its involvement in specialized immune responses within the gastrointestinal tract.

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