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當前位置:首頁產(chǎn)品中心抗體/抗原流式抗體S0B5257Pacific Blue Armenian hamster Anti-Mouse CD103 Antibody (S-R692)

Pacific Blue Armenian hamster Anti-Mouse CD103 Antibody (S-R692)
產(chǎn)品簡介:

Pacific Blue Armenian hamster Anti-Mouse CD103 Antibody (S-R692)

產(chǎn)品型號:S0B5257

更新時間:2025-07-12

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CD103, also known as integrin αEβ7, is a transmembrane heterodimer complex primarily expressed on the surface of various immune cells, including intraepithelial lymphocytes (IELs), tissue-resident memory T cells (TRM), and dendritic cells. It plays a crucial role in cell adhesion and migration through its interaction with E-cadherin, a cellular adhesion molecule found on epithelial cells. CD103 is a hallmark of immune cells residing in mucosal tissues such as the gut, lung, and skin, and is involved in immune surveillance and regulation. In cancer, CD103+ immune cells are associated with immune checkpoint pathways and can serve as predictive markers for immunotherapy response in various malignancies.

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