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S0B5257Pacific Blue Armenian hamster Anti-Mouse CD103 Antibody (S-R692)
產(chǎn)品型號:S0B5257
更新時間:2025-07-12
廠商性質(zhì):生產(chǎn)廠家
訪問量:31
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產(chǎn)品分類
CD103, also known as integrin αEβ7, is a transmembrane heterodimer complex primarily expressed on the surface of various immune cells, including intraepithelial lymphocytes (IELs), tissue-resident memory T cells (TRM), and dendritic cells. It plays a crucial role in cell adhesion and migration through its interaction with E-cadherin, a cellular adhesion molecule found on epithelial cells. CD103 is a hallmark of immune cells residing in mucosal tissues such as the gut, lung, and skin, and is involved in immune surveillance and regulation. In cancer, CD103+ immune cells are associated with immune checkpoint pathways and can serve as predictive markers for immunotherapy response in various malignancies.
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