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S0B5263Alexa Fluor? 488 Mouse Anti-Human CD7 Antibody (S-575-58)
產(chǎn)品型號(hào):S0B5263
更新時(shí)間:2025-07-12
廠商性質(zhì):生產(chǎn)廠家
訪問量:36
15855403091
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CD7, also known as GP40, is a transmembrane glycoprotein and a member of the immunoglobulin superfamily, primarily expressed on the surface of T cells and natural killer (NK) cells. It is highly expressed in acute T-cell leukemia (T-ALL) and certain peripheral T-cell lymphomas. CD7 plays a significant role in the regulation and activation of the immune system. It is involved in T-cell and T-cell/B-cell interactions during early lymphoid development and acts as a co-stimulatory molecule with CD3, CD45, and PI3K. CD7 has two known ligands, K12 protein and galectin-1, which can influence T cell proliferation, migration, and apoptosis. Additionally, CD7 is being explored as a target for cancer therapies, such as antibody-drug conjugates, due to its high expression in certain malignancies.
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