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S0B5485Rat Anti-Mouse CD150 Antibody (S-R738)
產(chǎn)品型號(hào):S0B5485
更新時(shí)間:2025-07-13
廠商性質(zhì):生產(chǎn)廠家
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15855403091
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CD150, also known as SLAM (Signaling Lymphocytic Activation Molecule), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily and encoded by the SLAMF1 gene. It is primarily expressed on various hematopoietic cells, including T cells, B cells, natural killer cells, dendritic cells, monocytes, and macrophages. CD150 serves multiple functions: it acts as a co-stimulatory molecule in immune cell activation, a receptor for morbilliviruses such as measles virus, and a bacterial sensor on macrophages. The protein has several isoforms, including a transmembrane form (mCD150), a secreted form (sCD150), and a novel transmembrane form (nCD150) with an alternative cytoplasmic tail. CD150 mediates homophilic interactions and can transmit either activating or inhibitory signals depending on the cell type and context.
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