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S0B5506FITC Mouse Anti-Rat CD68 Antibody (S-R674)
產(chǎn)品型號:S0B5506
更新時間:2025-07-13
廠商性質(zhì):生產(chǎn)廠家
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The CD68 protein is a heavily glycosylated transmembrane protein belonging to the lysosome-associated membrane glycoprotein (LAMP) family, primarily serving as a macrophage marker. With a molecular weight of approximately 110 kDa, it contains scavenger receptor-like cysteine-rich domains and participates in innate immune responses by binding specific ligands such as oxidized low-density lipoprotein (oxLDL). Localized to lysosomal and endosomal membranes, CD68 plays a crucial role in antigen presentation, inflammatory responses, and tissue repair. It is commonly detected via immunohistochemistry (e.g., using the PG-M1 antibody) and is widely utilized to identify tumor-associated macrophages (TAMs) and assess pathological progression in chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis.