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當(dāng)前位置:首頁(yè)產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2046p75 NGF Receptor Recombinant Rabbit mAb(SDT-055-42)

p75 NGF Receptor Recombinant Rabbit mAb(SDT-055-42)
產(chǎn)品簡(jiǎn)介:

p75 NGF Receptor Recombinant Rabbit mAb(SDT-055-42)

產(chǎn)品型號(hào):S0B2046

更新時(shí)間:2025-07-13

廠商性質(zhì):生產(chǎn)廠家

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The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR bound other neurotrophins equally well as nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.

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