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S0B2101FOXP1 Recombinant Rabbit mAb (SDT-R053)
產(chǎn)品型號:S0B2101
更新時間:2025-07-13
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The FOXP subfamily is defined by four members (FOXP1–FOXP4). FOXPs function as transcription factors and possess distinct transcriptional regulatory and DNA-binding domains. The N terminus of FOXPs contains a transcriptional repressor region with a zinc-finger/leucine zipper motif. The DNA-binding domain of FOXPs is uniquely positioned among forkhead proteins near the C terminus. FOXP1 is widely expressed in human tissues and regulates the development of many tissues, including heart, thymus, and lung. FOXP1-deficient embryos have severe defects in cardiac morphogenesis, including outflow tract septation and cushion defects, resulting in embryonic death.
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