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S0B2190Nectin-4 Recombinant Rabbit mAb (SDT-277-229)
產(chǎn)品型號:S0B2190
更新時間:2025-07-13
廠商性質(zhì):生產(chǎn)廠家
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The Nectin cell adhesion molecule (Nectin) family members are Ca2+?independent immunoglobulin?like cellular adhesion molecules (including Nectins 1?4), involved in cell adhesion via homophilic/heterophilic interplay. In addition, the Nectin family plays a significant role in enhancing cellular viability and movement ability. In contrast to enrichment of Nectins 1?3 in normal tissues, Nectin?4 is particularly overexpressed in a number of tumor types, including breast, lung, urothelial, colorectal, pancreatic and ovarian cancer. Moreover, the upregulation of Nectin?4 is an independent biomarker for overall survival in numerous cancer types [PMID: 34664682].
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