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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2234B7-H4 Recombinant Rabbit mAb (SDT-314-447)
產(chǎn)品型號：S0B2234
更新時間：2025-07-13
廠商性質：生產(chǎn)廠家
訪問量：35
服務熱線15855403091
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相關文章
B7-H4 is a transmembrane protein that binds an unknown receptor on activated T cells resulting in inhibition of T-cell effector function via cell cycle arrest, decreased proliferation, and reduced IL-2 production. B7-H4 is up-regulated on the surface of cancer cells and immunosuppressive tumor-associated macrophages （TAMs） in a variety of human cancers. Notably, B7-H4 expression levels inversely correlate with patient survival in ovarian cancer, cholangiocarcinoma, breast cancer and endometrial cancer, making B7-H4 an attractive candidate for therapeutic intervention.
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