MUC4 Recombinant Rabbit mAb (SDT-841-13)

產(chǎn)品型號：S0B2294

更新時間：2025-07-14

廠商性質(zhì)：生產(chǎn)廠家

訪問量：36

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

Mucin 4 （MUC4） is a highly glycosylated type I transmembrane glycoprotein. Normally acts as barrier to apical surface of epithelial cells, playing a protective and regulatory role. MUC4 expression is erroneous in many carcinomas and sarcomas, including sclerosing epithelioid fibrosarcoma and pancreatic adenocarcinoma. Immunohistochemical staining for MUC4 has been discussed as a potential biomarker for detection of these cancers. MUC4 can serve as a ligand for the oncogenic receptor ErbB2 and a modulator of its phosphorylation and signaling. MUC4 is frequently aberrantly expressed in epithelial tumors and can promote tumor growth and metastasis.

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