CD117 Recombinant Rabbit mAb (Alexa Fluor? 594 Conjugate) (S-125-51)

產(chǎn)品型號：S0B1556

更新時間：2025-07-14

廠商性質(zhì)：生產(chǎn)廠家

訪問量：41

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

TDP-43與漸凍癥：守護or背叛？

細胞外基質(zhì)（ECM）對上皮-間充質(zhì)轉(zhuǎn)化（EMT）作用影響解析

p16/Ki-67雙染：子宮頸癌前病變診斷的精準之道

Fibronectin：細胞培養(yǎng)的黏附大師

產(chǎn)品介紹

Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 （cluster of differentiation 117） or mast/stem cell growth factor receptor （SCFR）. Altered forms of this receptor may be associated with some types of cancer. KIT is a receptor tyrosine kinase type III, which binds to stem cell factor, also known as "steel factor" or "c-kit ligand" and expressed on the surface of hematopoietic stem cells as well as other cell types. When this receptor binds to stem cell factor （SCF） it forms a dimer that activates its intrinsic tyrosine kinase activity, that in turn phosphorylates and activates signal transduction molecules that propagate the signal in the cell. After activation, the receptor is ubiquitinated to mark it for transport to a lysosome and eventual destruction. Signaling through KIT plays a role in cell survival, proliferation, and differentiation. For instance, KIT signaling is required for melanocyte survival, and it is also involved in haematopoiesis and gametogenesis.

上一個：S0C2022B7-H3, CD4, CD66b, CD163, CD8α Antibody Panel