p53 Recombinant Rabbit mAb (Alexa Fluor??555 Conjugate) (SDT-R118)

產(chǎn)品型號：S0B1569

更新時間：2025-07-14

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

P53 is a gene that encodes for the p53 tumor suppressor protein, commonly referred to as the “Guardian of the Genome" [PMID: 1614522]. The p53 protein is a transcription factor that controls the output of many biological processes according to the type of cellular stress signal input. Stress signals known to activate p53 include oncogene activation, DNA damage, and replication stress [PMID: 28886379]. In response to these stresses, p53 undergoes post-translational modifications, promotes the transcription of genes involved in specific cell responses according to the stress type thereby controlling the cell’s fate [PMID: 15510160]. When the p53 protein is mutated or aggregated, it loses its function, resulting in tumor progression and growth [PMID: 29789497].

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