Alexa Fluor? 488 Mouse anti Human CD45RO (S-R401)

產(chǎn)品型號(hào)：S0B1703

更新時(shí)間：2025-07-14

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

CD45RO is an important cell surface marker in immunology that belongs to the CD45 family （also known as Leukocyte Common Antigen, LCA）. CD45 is a highly polymorphic transmembrane protein primarily expressed on the surface of white blood cells, including T cells, B cells, natural killer （NK） cells, monocytes, and granulocytes, and plays a crucial role in lymphocyte development, activation, and signaling. Specifically, CD45RO is an isoform of CD45 that is highly expressed on memory T cells but expressed at lower levels or not expressed on naive T cells. Memory T cells are T cells that have been activated and survived during previous immune responses, enabling them to rapidly and strongly activate upon re-encountering the same antigen, thus accelerating and enhancing immune responses. Therefore, CD45RO is often used to distinguish and identify memory T cells. It serves as an important marker in immune phenotyping analysis, disease diagnosis, immune response monitoring, and immunotherapy research.

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