国产免费一区不卡在线 - 久久青草精品38国产 - 伊人亚洲综合久久精品 - J妓女网站在线观看国产

13774214275
PRODUCT CENTER

產(chǎn)品中心

當前位置:首頁產(chǎn)品中心抗體/抗原ELISA試劑盒S0C3049Human&Mouse&Rat NFL OneStep ELISA Kit

Human&Mouse&Rat NFL OneStep ELISA Kit
產(chǎn)品簡介:

Human&Mouse&Rat NFL OneStep ELISA Kit

產(chǎn)品型號:S0C3049

更新時間:2025-07-15

廠商性質(zhì):生產(chǎn)廠家

訪問量:126

服務熱線

15855403091

立即咨詢
產(chǎn)品介紹

The Neurofilament Light Chain (NfL), a ~68 kDa protein encoded by the NEFL gene, is a critical structural component of the neuronal cytoskeleton, predominantly expressed in large myelinated axons of the central and peripheral nervous systems. As part of the neurofilament family (including NfM and NfH chains), NfL forms heteropolymers that stabilize axonal structure, regulate axon diameter to modulate nerve conduction velocity, and facilitate intracellular transport by acting as a scaffold for organelles and signaling molecules. Its release into biofluids (e.g., cerebrospinal fluid and blood) following neuronal injury or degeneration has established NfL as a highly sensitive, disease-agnostic biomarker of neuroaxonal damage. Elevated NfL levels correlate with diverse neurological conditions, including neurodegenerative diseases (Alzheimer’s, Parkinson’s, ALS), neuroinflammatory disorders (multiple sclerosis, neuromyelitis optica), stroke, and traumatic brain injury. Notably, NfL rises before clinical symptoms emerge, enabling early detection, while baseline concentrations predict disease progression and outcomes. Reductions in NfL levels are increasingly used to monitor therapeutic efficacy in clinical trials, such as antisense oligonucleotide therapies for ALS. Ultrasensitive assays like Simoa allow noninvasive blood-based quantification, enhancing its utility for longitudinal monitoring. With high sensitivity, accessibility, and broad applicability, NfL has become pivotal in advancing diagnostics, prognostics, and personalized treatment strategies for neurological disorders.

在線留言

ONLINE MESSAGE

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細地址:

  • 補充說明:

  • 驗證碼:

    請輸入計算結(jié)果(填寫阿拉伯數(shù)字),如:三加四=7
聯(lián)系方式

15855403091

(全國服務熱線)

浙江省杭州市上城區(qū)同協(xié)路1279號西子智慧產(chǎn)業(yè)園7號樓4層

wangxm@starter-bio.com

關(guān)注公眾號

Copyright © 2025杭州斯達特生物科技有限公司 All Rights Reserved   工信部備案號:

技術(shù)支持:化工儀器網(wǎng)   管理登錄   sitemap.xml

關(guān)注

聯(lián)系
聯(lián)系
頂部