Keratinocyte growth factor （KGF）, also known Fibroblast growth factor 7 （FGF-7） is a member of the fibroblast growth factor （FGF） family, and plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. KGF is also a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblast and endothelial cells. Studies of mouse and rat homologous protein implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.