Alexa Fluor? 647 Rat Anti-Mouse CD274/B7-H1/PD-L1 Antibody (S-R072)

產(chǎn)品型號：S0B5429

更新時間：2025-07-13

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

PD-L1, also known as CD274 or B7-H1, is a type I transmembrane glycoprotein and a member of the B7 family. It was first identified in 1999. PD-L1 plays a crucial role in immune regulation by binding to PD-1 on T cells, inhibiting their activation and proliferation through multiple pathways, thus dampening tumor-reactive T cell responses. This protein is widely expressed in various cells, including antigen-presenting cells, activated T cells, B cells, and some non-hematopoietic cells. Its expression is often upregulated in tumor cells, contributing to immune evasion. Targeting PD-L1 has become a major strategy in cancer immunotherapy, with several antibodies developed to block its interaction with PD-1, enhancing anti-tumor immunity.

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