Alexa Fluor? 647 Rat Anti-Mouse CD185 Antibody (S-R600)

產(chǎn)品型號：S0B5422

更新時間：2025-07-13

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

CD185, also known as CXCR5 or Burkitt lymphoma receptor 1 （BLR1）, is a G protein-coupled receptor with seven transmembrane regions. It belongs to the CXC chemokine receptor family and specifically binds to the chemokine CXCL13. This protein is crucial for the migration of B cells into B cell follicles in the spleen and Peyer's patches, and it is also essential for the function of follicular helper T cells. CD185 is expressed in mature B cells, follicular helper T cells, and certain types of lymphoma, including Burkitt's lymphoma. Additionally, it may play a role in maintaining cardiac structure under pressure overload and in the formation of ectopic mucosa-associated lymphoid tissue during chronic inflammation.

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